Classified

Date Posted: 06-01-2022 02:35 PM    Location: shijiazhuang, Kelantan    Posted by: yang summer    Views: 408 times

Gs-441524 is phosphorylated into nucleoside monophosphate (NMP) by cytokinase in cells, and then transformed into an active triphosphate metabolite (NTP structural analogue). In viral RNA synthesis, the active NTP analogues compete with the naturalnucleosides (ATP, TTP, CTP, GTP) to participate in RNA transcription. When gs-441524 is inserted into the transcription products, the transcription will be terminated in advance, thus inhibiting the viral RNA transcription process.When gs-441524 is inserted into the transcription products, the transcription will be terminated in advance, thus inhibiting the viral RNA transcription process.

Visit Website